Synthesis of C-homoaporphines via microwave-assisted direct arylation
نویسندگان
چکیده
منابع مشابه
Allocolchicinoid synthesis via direct arylation.
[reaction: see text] A formal enantioselective synthesis of allocolchicine and a synthesis of a C-ring analogue have been achieved by employing an intramolecular direct arylation of an aryl chloride to form the biaryl carbon-carbon bond and the seven-membered ring.
متن کاملMicrowave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KOtBu promoted intramolecular C-H arylation.
A simple, efficient, rapid and transition metal-free methodology has been developed by utilizing vasicine (a natural product), as a catalyst for the synthesis of phenanthridinones and dihydrophenanthridines. The reaction proceeds through intramolecular C-H arylation with aryl halides in the presence of KOtBu as a base under microwave irradiation in sulfolane as a solvent. The reaction proceeds ...
متن کاملEfficient synthesis of polymethoxyselenoflavones via regioselective direct C-H arylation of selenochromones.
Substantial research has suggested that the configuration and the total number of functional groups on flavones influence their bioactivity. To investigate the changes in the biological activities of selenoflavones in relationship to structural changes, the development of a generally applicable synthetic method was a key. Until now, an efficient pathway for palladium-catalyzed direct arylation ...
متن کاملMicrowave-assisted synthesis of molybdenum oxide nanoparticles
This paper focused on a simple approach for synthesis of molybdenum oxide (MoO3) nanoparticles and reports a facile route for synthesis of such nanoparticles, using microwave irradiation as a homogenous and powerful source of heating, using ethylene glycol as the solvent and heating medium. For more investigations, besides microwave heating, the obtained solutions were also treated by conventio...
متن کاملPalladium-catalyzed microwave-assisted direct arylation of imidazo[2,1-b]thiazoles with aryl bromides: synthesis and mechanistic study.
A palladium-catalyzed direct C-H arylation of various imidazo[2,1-b]thiazoles with a range of aryl bromides under microwave irradiation is described. 6-Phenyl substituted imidazo[2,1-b]thiazoles could be regioselectively C-5 arylated using the developed protocol. The utility of this method enables the representative coupling product to be achieved by a sequential one-pot reaction. Density funct...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tetrahedron
سال: 2011
ISSN: 0040-4020
DOI: 10.1016/j.tet.2010.11.059